Synthetic Organic Chemistry Laboratory
Indian Institute of Science Education and Research Bhopal
From IISER Bhopal
[59] Prasenjit Gayen, Suman Sar, Prasanta Ghorai*, "Stereodivergent Synthesis of Spiroaminals via Chiral Bifunctional Hydrogen Bonding Organocatalysis"
Angew. Chem. Int. Ed. 2024, e202404106. This article appears in "Hot Topic: Organocatalysis".
[58] Chandan Kamilya, Sachin S. Gorad, Prasanta Ghorai*, "An Organocatalytic Highly Enantioselective Stereospecific Synthesis of 1,1-Disubstituted- 1,3-Dihydroisobenzofurans"
[57] Dipankar Das, Chandan Kamilya, Prasanta Ghorai*, "Hydrazine Hydrate in Asymmetric Synthesis: A Bifunctional Squaramide Catalytic Approach Towards Fused Pyrazolines"
[56] Abhisek Midya, Laxman Devidas Khalse, Prasanta Ghorai*, "Organocatalytic Enantioselective Intramolecular Michael Addition via In Situ Generated Aminoisobenzofulvenes: Construction of Spiro Quaternary Carbon Stereocenters"
[55] Suman Sar, and Prasanta Ghorai*, "Pd-Catalyzed Chemodivergent Synthesis of 1-Indanones via Diethyl Zinc-Mediated Precise Switching of Umpolung Reactivity"
[54] Shibaram Panda, and Prasanta Ghorai*, "Expedient Access to Enantioenriched 1-Azaspiro Cyclobutanones Enabled by Modified Heyns Rearrangement"
Angew. Chem. Int. Ed. 2023, e202306179. This article appeared in "Hot Topic: Organocatalysis".
[53] Prasenjit Gayen and Prasanta Ghorai*, "Enantioselective Synthesis of 1,3-Benzothiazine Derivatives: An Organocatalytic Chemoselective Approach" Org. Lett. 2023, 25, 3835–3840.
[52] Laxman Devidas Khalse and Prasanta Ghorai*, ''Stereoselective Borylcupration/Michael Addition on Symmetrical Dienones''
[51] Abhisek Midya, Laxman Devidas Khalse, and Prasanta Ghorai* ''Chiral Amine Catalyzed Reductive Aldol/Reductive Michael Addition Cascade Towards Enantioselective Synthesis of Benzannulated Diquinanes''
[50] Suman Sar and Prasanta Ghorai* ''An Intramolecular Umpolung Cascade Kukhtin–Ramirez Reaction/Michael Addition-Initiated Cyclization: Stereoselective Synthesis of Tetrasubstituted Cyclopropane Fused 1-Indanones''
[49] Shibaram Panda, Upasana Gayen, and Prasanta Ghorai* ''Organocatalytic Desymmetric Conjugate Addition of Cyclobutanone: An Enantio- and Diastereoselective Synthesis of [6,5,4]-Fused Carbocycles''
[48] Laxman Devidas Khalse, Sachin S. Gorad, and Prasanta Ghorai* ''Enantio- and Diastereoselective Cu(II)-Catalyzed Conjugate Borylation/Michael Addition Cascade: Synthesis of Spiroindane Boronates''
[47] Suman Sar and Prasanta Ghorai* ''Umpolung Chemo- and Regioselective Cascade Addition of Diethylzinc to α-Diketones Followed by Intramolecular Michael Reaction: Stereoselective Synthesis of Highly Substituted 1- Indanones''
[46] Tarun Kumar Roy, Sachin S. Gorad, and Prasanta Ghorai* ''Chiral Squaramide Catalyzed Asymmetric Spiroketalization toward Aromatic [6,5] Spiroketals''
[45] Rajasekhar R. Reddy, Prasenjit Gayen, Shibaram Panda and Prasanta Ghorai* ''Enantioselective, organocatalytic, dissymmetric 1, 4-and 1, 2-addition of malononitrile to a keto-bisenone followed by an oxa-Michael addition cascade''
[44] Rajasekhar R. Reddy, Shibaram Panda and Prasanta Ghorai* ''Enantioselective Synthesis of Cyclohexadienone Containing Spiroketals via DyKat Ketalization/oxa-Michael Addition Cascade''
[43] Gurupada Hazra, Shiv Pratap, and Prasanta Ghorai* ''Organocatalytic, Chemoselective Hydrophosphenylation/oxa-Michael Addition Cascade toward Diastereo- and Enantioenriched 1,3-Dihydroisobenzofuryl Phosphonates''
[42] Tarun Kumar Roy, Biswajit Parhi, and Prasanta Ghorai* ''Cinchonamine-Squaramide Catalyzed Asymmetric aza-Michael Reaction: Dihydroisoquinolines and Tetrahydropyridines''
[41] Sanjay Maity, Suman Sar and Prasanta Ghorai* ''Primary Amino-thiourea Catalyzed Enantioselective Synthesis of Rauhut-Currier Adducts of 3-Arylcyclohexenone with a Tethered Enone on the Aryl Moiety at ortho-Position''
[40] Sanjay Maity, Mithu Saha, Gurupada Hazra and Prasanta Ghorai*, ''Switchable Chemoselectivity for Organocatalytic, Asymmetric Malononitrile Addition to ortho-Formyl Chalcones''
[39] Rajender Nallagonda, Reddy Rajasekhar Reddy, and Prasanta Ghorai*, "Nitrile-Assisted Oxidation over Oxidative-Annulation: Pd-Catalyzed α,β-Dehydrogenation of α-Cinnamyl β-Keto Nitriles" (Invited article: Mechanistic Aspects of Organic Synthesis)
[38] Reddy Rajasekhar Reddy, Komalkant Adlak, and Prasanta Ghorai*, "Catalyst-free Synthesis of 6-Hydroxy Indoles via the Condensation of Carboxymethyl Cyclohexadienones and Amines"
[37] Abhisek Midya, Sanjay Maity and Prasanta Ghorai*, "Dynamic Kinetic Spiroketalization/oxa-Michael Addition Cascade of Alkoxyboronates and Peroxy-Acetals: Enantio- and Diastereoselective Synthesis of Benzannulated Spiroketals"
[36] Mohammad Rehan, Rajender Nallagonda, Braja Gopal Das, Tannu Meena and Prasanta Ghorai*, "Synthesis of Functionalized Benzo[b]furans via Oxidative Cyclization of o-Cinnamyl Phenols"
[35] Gurupada Hazra, Sanjay Maity, Sudipto Bhowmick and Prasanta Ghorai*, "Organocatalytic, Enantioselective Synthesis of Benzoxaboroles via
Wittig/oxa‐Michael Reaction Cascade of α‐Formyl Boronic Acids"
[34] Reddy Rajasekhar Reddy, Satish Sonbarao Gudup, and Prasanta Ghorai*, "Organocatalytic, Enantioselective Synthesis of Cyclohexadienone
Containing Hindered Spirocyclic Ethers via Oxidative Dearomatization/oxa-Michael Addition Cascade"
Angew. Chem. Int. Ed. 2016, 55, 15115 –15119.
Highlighted in Synfacts, 2017, 13, 0088.
[33] Biswajit Parhi, Sanjay Maity, and Prasanta Ghorai*, "Catalytic Asymmetric Conjugate Addition of Carboxylic Acids via Oxa-Michael Reaction of Peroxy Hemiacetals followed by Kornblum DeLaMare Fragmentation"
[32] Biswajit Parhi, Jitendra Gurjar, Suman Pramanik, Abhisek Midya and Prasanta Ghorai*,
An Organocatalytic Enantioselective Intramolecular Oxa-Michael Reaction of Enols: Synthesis of Chiral Isochromenes
J. Org. Chem. 2016, 81 ,4654–4663.
[31] Mohammad Rehan, Sanjay Maity, Lalit Kumar Morya, Kaushik Pal and Prasanta Ghorai*,
Angew. Chem. Int. Ed. 2016, 55, 7728-7732.
[30] Sanjay Maity, Biswajit Parhi, and Prasanta Ghorai*,
Enantio- and Diastereoselective Synthesis of exo-Peroxyacetals: An Oranocatalyzed Peroxyhemiacetalization/oxa-Michael Addition Cascade Angew. Chem. Int. Ed. 2016, 55, 7723-7727.
[29] Rajender Nallagonda, Reddy Rajasekhar Reddy, and Prasanta Ghorai*,
Chem. Eur. J. 2015, 21, 14732 –14736.
Highlighted in ChemInform, 2016, 47, 11 (DOI: 10.1002/chin.201611124).
[28] Braja Gopal Das, Rajender Nallagonda, Dhananjay Dey, and Prasanta Ghorai*,
Chem. Eur. J. 2015, 21, 12601 –12605.
Highlighted in Synfacts, 2015, 11, 1171.
Highlighted in ChemInform, 2015, 47, (DOI: 10.1002/chin.201602020).
[27] Barnala Ravindra, Sanjay Maity, Braja Gopal Das, and Prasanta Ghorai*,
J. Org. Chem. 2015, 80, 7008–7018.
Highlighted in Synfacts, 2015, 11, 1023.
Highlighted in ChemInform, 2015, 46, (DOI: 10.1002/chin.v46.47).
[26] Suman Pramanik, Reddy Rajasekhar Reddy and Prasanta Ghorai*,
Intramolecular Rearrangement of α-Azidoperoxides: An Efficient Synthesis of tert-Butyl Esters
Org. Lett. 2015, 17, 1393-1396. [Abstract]
$ Among the Top 20 most read articles April 2015
[25] Mohammad Rehan, Gurupada Hazra and Prasanta Ghorai*,
Org. Lett. 2015, 17, 1668-1671. [Abstract]
$ Among the Top 20 most read articles March-April 2015
Highlighted in ChemInform, 2015, 46, (DOI: 10.1002/chin.201533200).
[24] Suman Pramanik, Reddy Rajasekhar Reddy and Prasanta Ghorai*,
J. Org. Chem. 2015, 80, 3656-3663. [Abstract]
Highlighted in ChemInform, 2015, 46, (DOI: 10.1002/chin.201533091).
[23] Barnala Ravindra, Braja Gopal Das and Prasanta Ghorai*,
Org. Lett. 2014, 16, 5580-5583. [Abstract]
Highlighted in ChemInform, 2015, 46, (DOI: 10.1002/chin.201517135)
[22] Rajender Nallagonda, Mohammad Rehan and Prasanta Ghorai*,
Synthesis of Functionalized Indoles via Palladium-Catalyzed Aerobic Oxidative Cycloisomerization of o-Allylanilines
Org. Lett. 2014, 16, 4786-4789. [Abstract]
$ Among the most read articles September 2014
Highlighted in ChemInform, 2015, 46 (10.1002/chin.v46.12)
[21] Rajender Nallagonda, Mohammad Rehan and Prasanta Ghorai*,
Chemoselective C-Benzylation of Unprotected Anilines with Benzyl Alcohols Using Re2O7 Catalyst
J. Org. Chem. 2014, 79, 2934-2943. [Abstract]
[20] Suman Pramanik and Prasanta Ghorai*,
Trapping of Azidocarbenium Ion: A Unique Route for Azide Synthesis
Org. Lett. 2014, 16, 2104-2107. [Abstract]
Highlighted in Synfacts, 2014, 10, 582.
[19] Suman Pramanik and Prasanta Ghorai*,
Chemoselective three-component synthesis of homoallylic azides using an FeCl3 catalyst
RSC Adv. 2013, 3, 23157-23165. [Abstract]
[18] Suman Pramanik and Prasanta Ghorai*,
Synthesis and Asymmetric Resolution of α-Azido-peroxides
Org. Lett. 2013, 15, 3832-3835. [Abstract]
[17] Braja Gopal Das and Prasanta Ghorai*,
Stereoselective Direct Reductive Amination of Ketones with Electron-deficient Amines using Re2O7/NaPF6 Catalyst
Org. Biomol. Chem. 2013, 11. 4379-4382. [Abstract]
[16] Braja Gopal Das and Prasanta Ghorai*,
The Direct Reductive Amination of Electron-deficient Amines with Aldehydes: the Unique Reactivity of Re2O7 Catalyst
Chem. Comm. 2012, 48. 8276-8278. [Abstract]
Highlighted in ChemInform, 2012 (DOI: 10.1002/chin.201250035)
[15] Braja Gopal Das, Rajendra Nallagonda, and Prasanta Ghorai*,
Direct Substitution of Hydroxy Group of π-Activated Alcohols with Electron Deficient Amines using Re2O7 Catalyst
J. Org. Chem. 2012, 77, 5577-5583. [Abstract]
Highlighted in ChemInform, 2012 (DOI: 10.1002/chin.201244046)
[14] Suman Pramanik and Prasanta Ghorai*,
Re2O7-Catalyzed Three-Component Synthesis of Protected Secondary and Tertiary Homoallylic Amines,
Chem. Comm. 2012, 48, 1820-1822. [Abstract]
Highlighted in ChemInform, 2012 (DOI: 10.1002/chin.201222062)
From UNL, USA
[13] Jiliang Hang, Prasanta Ghorai, Solaire A Finkenstaedt-Quinn, Ilhan Findik, Emily Sliz, Keith T Kuwata. Patrick H Dussault,
Generation of Singlet Oxygen from Fragmentation of Monoactivated 1,1-Dihydroperoxides
J. Org. Chem. 2012, 77, 1233–1243.
[12] Prasanta Ghorai, Patrick H Dussault,
A New Peroxide Fragmentation: Efficient Chemical Generation of 1O2 in Organic Media
Org. Lett. 2009, 11, 4572–4575.
[11] Prasanta Ghorai, Patrick H. Dussault,
Broadly Applicable Synthesis of 1,2,4,5-Tetraoxanes
Org. Lett. 2009, 11, 213–216.
[10] Prasanta Ghorai, Patrick H. Dussault,
Mild and Efficient Re(VII)-Catalyzed Synthesis of 1,1-Dihydroperoxides
Org. Lett., 2008, 10, 4577–4579.
[09] Prasanta Ghorai, Patrick H Dussault, Chunhua Hu,
Synthesis of Spiro-bisperoxyketals
Org. Lett. 2008, 10, 2401–2404.
From UR Germany
[08] Ghorai P, Kraus A, Birnkammer T, Geyer R, Bernhardt G, Dove S, Seifert R, Elz S, Buschauer A,
Chiral NG-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity
Bioorg. Med. Chem. Lett. 2010, 20, 3173-3176.
[07] Kraus A, Ghorai P, Birnkammer T, Schnell D, Elz S, Seifert R, Dove S, Bernhardt G, Buschauer A.
N(G)-acylated aminothiazolylpropylguanidines as potent and selective histamine H(2) receptor agonists.
ChemMedChem. 2009, 4, 232-240.
[06] Prasanta Ghorai, Anja Kraus, Max Keller, Carsten Götte, Patrick Igel, Erich Schneider, David Schnell,Günther Bernhardt, Stefan Dove, Manfred Zabel, Sigurd Elz, Roland Seifert and Armin Buschauer
Acylguanidines as Bioisosteres of Guanidines: NG-Acylated Imidazolylpropylguanidines, a New Class of Histamine H2 Receptor Agonists
J. Med. Chem. 2008, 51, 7193–7204.
[05] Hendrik P, Ghorai P, Kraus A, Dove S, Buschauer A, Seifert R,
Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affects the Species Selective Activity of Guadine-Type
Naunyn Schmiedebergs Arch Pharmacol 2007, 376, 253-264.
[04] Hendrik P, Ghorai P, Kraus A, Dove S, Buschauer A, Seifert R.
Constitutive activity and ligand selectivity of human, guinea pig, rat, and canine histamine H2 receptors.
J Pharmacol Exp Ther. 2007, 321, 983-995.
[03] Preuss H, Ghorai P, Kraus A, Dove S, Buschauer A, Seifert R.
Mutations of Cys-17 and Ala-271 in the human histamine H2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity
J Pharmacol Exp Ther. 2007, 321, 975-982.
[02] Xie SX, Ghorai P, Ye QZ, Buschauer A, Seifert R.
Probing ligand-specific histamine H1- and H2-receptor conformations with NG-acylated Imidazolylpropylguanidines.
J Pharmacol Exp Ther. 2006, 317, 139-146.
[01] Xie SX, Kraus A, Ghorai P, Ye QZ, Elz S, Buschauer A, Seifert R.
N1-(3-cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-yl)propyl]guanidine (UR-AK57), a potent partial agonist for the human histamine H1 and H2- receptors.
J. Pharmacol Exp Ther. 2006, 317, 1262-1268.